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WINCAL BIOPHARM, INC.
Open Positions
Scientist in Pharmacology
Full Time
We are seeking a Scientist to join us to drive translational projects enabling rodent preclinical efficacy studies on vascular disease models. The Scientist will conduct studies independently or in collaboration with other scientists to monitor in vivo efficacy for therapeutic candidate molecules and to analyze ex vivo tissue samples. Compensation and title commensurate with experience.
Responsibilities:
Design and execution of studies in mouse aneurysm models
Perform different routes of injections including IV, SC or IC
Isolate tissues including organs and blood vessels
Perform tissue imaging and analyze data
Document experiments and write study reports
Required Skills/Experience:
A Ph.D. degree in biological sciences, pharmacology, veterinary sciences or equivalent
Willingness to learn and perform in vitro and in vivo studies
Previous experience with mouse models is preferred, but not required
Ability to independently investigate and propose new methods and applications
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Wincal Biopharm is an Equal Opportunity Employer and prohibits. Wincal is committed to the principle of equal employment opportunity for all employees.
Scientist in Biology
Full Time
We are seeking a Scientist who will conduct studies independently or in collaboration with other scientists to support a drug delivery platform and characterize biochemical properties for therapeutic candidate molecules. Compensation and title commensurate with experience.
Responsibilities:
Assist tissue sampling process and analyze the samples.
Design and execute biochemical assays (ELISA, WB, protein, cell quantitation)
Fluorescent labeling of proteins and antibodies
Prepare for test formulation
Perform cellular and molecular characterization of specimens
Document experiments and write study reports
Required Skills/Experience:
A PhD degree in biological sciences, pharmacology or equivalent
A quick learner for new areas
Willingness to learn and support other scientists and programs
Ability to independently investigate and propose new methods, applications and drug targets
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Wincal Biopharm is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination.
Business Development Manager/Sr. Manager/Associate Director
Full Time
We are seeking a highly motivated individual to join as a Manager of Business Development. This role is a key member of the BD team and will contribute to the corporate activities related to partnering, collaboration and business strategies to maximize the value of our portfolio. The candidate will drive seeking partnering opportunities with big pharma industries and help deliver our corporate mission. The candidate will interact with senior management and R&D team leaders to align the BD direction and drive the growth of the company and progress of the pipeline.
Responsibilities:
Serve as a global business representative and lead partnership opportunities with pharma companies
Lead licensing activities for both in- & out-license and manage the deals
Lead BD efforts in the due diligence, evaluation and identification
Build networks with other pharma BD teams and manage accurate assessment
Manage board meeting materials and investor relations
Seek opportunities to align interests with business needs
Align with R&D teams to deliver corporate goals
Have an entrepreneurial mindset to support business decisions
Required Skills/Experience:
BS/BA (>5 years), MBA (>3 years), PhD/MD (>2 years) degrees with 3-7 years business development experience in biopharma industry or investment bank or management consulting firm
Previous experience with pharma partnering negotiation deals
Understanding of the drug development process, biologics, ocular and vascular disease related
Ability to independently investigate and propose new business models and applications
Experience or working knowledge of IP licensing deal is a plus
Wincal Biopharm is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment. Compensation and title commensurate with experience.
Postdoctoral Staff
Full Time
We are seeking an industry postdoc to study the mechanism of action for our novel therapeutic antibody. The project is to support a translational project focusing on smooth muscle cells and endothelial cells expanding to rodent preclinical efficacy studies vascular aneurysm models. The candidate will conduct studies independently or in collaboration with other scientists to monitor in vitro and ex vivo tissue analyses.
Responsibilities:
Design and execution of cell-based biochemical analyses to address MoA
Apply and confirm the discoveries from cell studies to the mouse model(s) and ex vivo analysis
Histological analysis of tissues including organs and blood vessels
Summarize study reports and write a manuscript
Required Skills/Experience:
PhD in biological sciences or any equivalent credentials
Experience in angiogenesis, cytokine, efferocytosis or vascular biology related
Willing to learn standard vascular assessment techniques (vascular plaque analysis, macrophage efferocytosis, vascular leakiness in animal models)
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Wincal Biopharm is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment. Compensation and title commensurate with experience.
In Vivo Scientist
Full Time
We are seeking a scientist to drive translational projects enabling rodent preclinical efficacy studies on ocular gene therapy and/or vascular aneurysm models. The candidate will conduct studies independently or in collaboration with other scientists focused on eyedrop gene delivery to monitor in vivo efficacy and ex vivo tissue analyses.
Responsibilities:
Design and execution of gene therapy studies in mouse and rat models of laser-induced CNV
Develop mouse aneurysm model(s) and ex vivo analysis as a secondary responsibility
Perform different routes of injections including IV, SC, IC, IVT injections
Isolate tissues including organs, eyes, retina and blood vessels
Perform cellular and molecular characterization of specimens
Write a new animal study protocol for IACUC review
Document experiments and write study reports
Required Skills/Experience:
Ph.D. degree in biological sciences, pharmacology, veterinary sciences or equivalent with 2-3 years postdoc in academia or industry with experience in animal studies
Expertise in ophthalmological studies and ocular gene therapy (AAV, siRNA, DNA/RNA)
Previous experience with aortic vascular aneurysm is a plus: Experience with standard vascular assessment techniques (vascular plaque analysis, macrophage efferocytosis, vascular leakiness in animal models)
Mouse injections and tissue processing experience
Ability to independently investigate and propose new methods and applications
Experience or working knowledge of Micron OCT imaging is a plus
Wincal Biopharm is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment. Compensation and title commensurate with experience.
Research Associate/Sr. RA/Associate Scientist
Full Time
The candidate will be working with senior scientists and assisting laboratory activity including biochemical and bioimaging analysis for therapeutic reagents. The candidate may have an opportunity to learn vascular disease related analyses.
Required Skills/Experience
BS or MS in Biological Sciences, biomedical, bioengineering, pharmacology or related subjects.
Enthusiastic and willingness to learn and explore new methods and studies.
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Wincal Biopharm is committed to the principle of equal employment opportunity for all employees. Compensation and title commensurate with experience.